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Shaikh Zinnat Ara Nasreen

ZH Shikder Women's Medical College & Hospital, Bangladesh

Title: All about MHT (Menopause Hormone Therapy)

Abstract

Background: MHT was the standard of care for menopause until 2002. Following Women's Health Initiative (WHI) trial findings, perceptions changed. Fears of breast cancer and cardiovascular disease of WHI study, were not supported by reanalysis of data by IMS 2013, especially for recently menopausal women. The WHI tested MHT started a decade or more after menopause so results were biased. Age at starting MHT is critical in determining the benefit/risks. Diminished MHT use following the WHI report prompted strong interests in alternative treatments. None provided the range of benefits across multiple organ systems offered by MHT (estrogen). Most have concerning adverse effects in their own right. MHT can provide effective relief for a wide range of health conditions, potentially avoiding the need for multiple treatments for separate problems. Unfortunately, among many women and clinicians, the perception of MHT benefit/risk is distorted, and its use avoided, leading to unnecessary distress for menopause women. When MHT is initiated within 10 years of menopause or below the age of 60 years (Timing Hypothesis), MHT reduces all-cause mortality and risks of coronary disease, osteoporosis, dementias and vasomotor symptoms. 
Conclusion: MHT starting at this window opportunity with minimum dose, maximize the benefits and minimize the risks, nevertheless MHT should be given to women for clear indication to improve her QoL. She should be informed about all the proses and cones of the MHT so that she would be empowered to have shared decision with her health care providers.

Biography

Shaikh Zinnat Ara Nasreen is a Gynecologist in Dhaka. Her qualification is MBBS, FCPS (OBGYN), MRCOG (London), FRCOG (London). She is a Professor and head of the Department of Gynecology & Obstetrics at ZH Sikder Women's Medical College & Hospital.