Archi Ghanti
Madras Medical Mission Hospital, IndiaTitle: Relation between serum hormones & semen parameters in sub-fertile males: Is 17-OHP really a game changer?
Abstract
Our study was designed to find relationship between individual serum hormone levels & semen parameters in sub-fertile men, and to find whether 17 OHP fares better or worse in predicting baseline semen parameters compared to other routinely tested hormones (serum FSH, total testosterone, estradiol). A retrospective analytical study was conducted on 74 patients obtained, after matching inclusion & exclusion criteria, from July 2022-December 2023. Only 10 patients (13.51%) had normal semen analysis, while rest 64 (86.49%) had abnormality in at least 1 semen parameter. Serum Testosterone & T/E2 ratio had significant difference (p<0.05) between two groups. Comparing individual semen parameters against all hormones, FSH and Total Testosterone had significant association with Sperm Count, Concentration & total motility. Total Testosterone also had a significant relation with Progressive Motility, Morphology and Semen volume (p<0.05). T/E2 ratio had significant association with Sperm count, motility & morphology, and semen volume (p<0.05). But, 17-OHP & Estradiol were not found to have any significant association with any baseline Semen Parameters in our study (p>0.05). But, serum 17OHP was found to be significantly associated with sexual dysfunction in males (p<0.05) & thus it can serve as a novel marker for male sexual dysfunction.
Biography
Archi Ghanti has completed her MBBS from Calcutta Medical College & MS in Obstetrics & Gynaecology from R. G. Kar Medical College, Kolkata, India. Currently she is a post-Doctoral fellow of Reproductive Medicine, at Madras Medical Mission Hospital, Chennai, India. She has 5 publications in National & International journals. She is an avid quizzer & has won several awards at National quizzes.
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